Intracytoplasmic Sperm Injection

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Intracytoplasmic Sperm Injection

Intracytoplasmic sperm injection (ICSI) is a specialized form of IVF treatment that involves injecting a single sperm into each egg using very fine micromanipulation equipment.

As the human egg is one-tenth of a millimeter in diameter and the sperm 100 times smaller this is a very delicate procedure performed by highly skilled embryologists using a sophisticated microscope.

Intracytoplasmic Sperm Injection
Intracytoplasmic Sperm Injection

How does ICSI work?

The procedure of ICSI involves direct injection of a single sperm into an egg under the microscope. When there is little or no sperm in the ejaculate (oligo or azoospermia), ICSI can be performed to accomplish fertilization with sperm obtained through microsurgical epididymal sperm aspiration (MESA), testicular sperm extraction (TESE), or testicular sperm aspiration (TESA).

ICSI has not been shown to increase fertilization rates in situations where the sperm assessment is normal. Normal fertilization rates with IVF or ICSI are approximately 50-60%. That is, for every 10 mature eggs obtained and combined with the sperm either with IVF or ICSI, approximately five to six will fertilize normally.

After the eggs are retrieved, instead of mixing the sperm with the egg, the embryologist utilizes a thin glass pipette to immobilize the sperm, sucks it up into the pipette, and then injects it directly into the egg’s cytoplasm.

If there is evidence of poor outcomes with previous ICSI treatment, your Footsteps To Fertility Clinic specialist in Kenya may recommend you undergo Intracytoplasmic morphologically selected sperm injection (IMSI) to improve your chances of pregnancy success.

Who requires Intracytoplasmic Sperm Injection?

For many couples where sperm quality is poor, conventional IVF is unlikely to result in fertilization. In such cases, your fertility specialist will recommend IVF with ICSI.

Intracytoplasmic Sperm Injection is a technique incorporated into IVF infertility treatment in situations where the male partner suffers from any of the following:

  • no sperm noted on a semen sample
  • low sperm count
  • high presence of abnormal sperm
  • low sperm motility
  • inability to ejaculate sperm
  • ICSI may also be recommended for couples who have been unsuccessful with previous IVF cycles, and couples with unexplained infertility

Possible risks and complications

For the egg:

As ICSI is more invasive and requires more handling than standard IVF insemination techniques, there is a small chance (less than 2%) that the egg may be damaged during the procedure – resulting in a non-viable egg.

For the resulting child:

Thousands of children around the world have been born as a result of ICSI. So far, there is no convincing evidence that the incidence of birth defects is any different with ICSI or IVF compared with children born to other parents of similar age and health.

The mother’s age at delivery, family history and the presence of pregnancy complications are the most important predictors of newborn health. However, it is possible that a male child born as a result of ICSI might have a fertility problem similar to his father’s.

At Footsteps To Fertility, there is no one-size-fits-all approach when it comes to infertility. From artificial insemination procedures like IUI to the latest IVF technology, our focus is on helping families grow with safe and proven solutions that require less stress on the mind and body.

Feel free to contact us, chat with us or directly reserve an appointment below. We are always there when you need us.

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