What Causes Recurrent Pregnancy Loss?
Most miscarriages occur due to abnormal genes or chromosomes that stop the fetus from normal growth and development. It’s important to know that these abnormal genes do not come from an inherited health condition.
About half of all miscarriages are associated with extra or missing chromosomes that happen by chance during fertilization. One common chromosomal cause, called translocation, occurs when separate chromosomes swap small segments, creating an abnormal area on each chromosome.
A variety of other conditions may cause repeated miscarriage. Abnormalities in the uterus — congenital problems that affect the structure of the uterus, uterine fibroids, polyps, and adhesions — are all associated with miscarriage.
Medical conditions can also increase the risk of miscarriage. Diabetes, polycystic ovary syndrome, hypothyroidism, and an autoimmune disorder called antiphospholipid syndrome represent some of the top medical causes.
In some cases, problems with the blood supply in the placenta lead to recurrent miscarriage.
Treatment of Recurrent Pregnancy Loss
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